85. Devenir histologique d’un biomatériau biphasé dans les comblements d’Ostéotomies d’ouverture tibiale - Clinical, radiological and histological evaluation of biphasic calcium phosphate bioceramic wedges filling medial high tibial valgisation osteotomies

JL Rouvillain, G Daculsi, Y Catonne, C Gane, C Zekhnini, E Garron
(Fort de France, Nantes)

We report clinical, radiological and histological findings following high tibial valgisation osteotomy (HTVO) using micro-macroporous biphasic calcium phosphate wedges fixed with a plate and locking screws. From 1999 to 2002, 43 knees were operated on and studied prospectively. All underwent clinical and radiological follow-up at days 1, 90, and 365 to evaluate consolidation and bone substitute interfaces. Additionally, biopsies were taken for histology at least 1 year after implantation from 10 patients who requested plate removal.

Radiologically, consolidation was observed in 98% of cases. At 1 year, correction was unchanged in 95% of cases. Histological analysis revealed considerable MBCP® resorption and bone ingrowth, both into the pores and replacing the bioceramic material. Polarised light microscopy confirmed normal bony architecture with trabecular and/or dense lamellar bone growth at the expense of the wedge implants. X-ray and micro-CT scan revealed a well organised and mineralised structure in the newly-formed bone.

This study shows that using MBCP® wedges in combination with orientable locking screws and a plate is a simple, safe and fast surgical technique for HTVO. This is the first study to examine the results by histological analysis, which confirmed good outcomes.

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